Researchers have found that ovarian cancer can mutate and can develop a mechanism to survive chemotherapy drugs and rebound. Ovarian cancer, dubbed as "silent killer" because of the number deaths attributed to the disease, is a major killer among women.

Two studies that was published online by the British Journal Nature has shown that ovarian tumors among women with cancer-causing gene called BRCA2, initially respond to treatment using platinum-based drugs like cisplatin and carboplatin.

However, there have been many documented cases that the tumor eventually develop resistance to these drugs.

Doctors said that BRCA2 type cancers responded to chemotherapy treatment. But gene mutations alters the BRCA2 ability to repair DNA damage caused by the cancer cells. It also allows cancer cells to survive and become resistant to platinum-based drugs.