Overweight men with elevated levels of insulin are at a higher risk of developing prostate cancer than other patients, a new Canadian study says.

Researchers at Montreal-based McGill University, in collaboration with Harvard University, analyzed data from 2,546 American men who were diagnosed with prostate cancer during 24 years of follow-up.

The results indicated that those who were overweight (with body mass index of 25-29.9) or obese (body mass index of 30 or higher) before diagnosis were much more likely to die of the disease than those of normal weight.

Those who were overweight and had high levels of a protein that rises with insulin secretion were four times more likely to die after a diagnosis of prostate cancer, the study found. The study has been published in the October issue of The Lancet Oncology.