Scientists at John Hopkins University are studying trials on pigs resulting in 50% to 75% restoration of their damaged hearts by transmitting adult stem cells transplanted from bone marrow.

Now, two patients have signed up for the human trials and are set to begin. According to the report, the study of 48 heart attack patients that will ultimately take part in the phase 1 study, which is designed to test the safety of injecting adult stem cells into their hearts.

Study leader Professor Joshua Hare says, "Ultimately, the goal is to develop a widely applicable treatment to repair and reverse the damage done to heart muscle that has been infarcted, or destroyed, after losing its blood supply. There is reason for optimism about these findings, possibly leading to a first-ever cure for heart attack in humans."