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 Human Immunodeficiency Virus Information - October 12, 2008
| World Health Organization researchers and colleagues on Monday reported that circumcising men routinely across Africa could prevent millions of deaths from AIDS. Researchers analyzed data from previous trials that showed circumcised men were at lesser risk of contracting infection with the AIDS virus, and calculated that if all men were circumcised over the next 10 years, some two million new infections and around 300,000 deaths could be avoided | | GlaxoSmithKline Plc plans to develop an experimental AIDS vaccine, using the measles. Europe's biggest drug maker and France's Institut Pasteur intend to develop the vaccine by fusing genes from the human immunodeficiency virus (HIV) onto an existing vaccine for the childhood disease. Glaxo's vaccines unit, GSK Biologicals, will license the measles vaccine carrier, technology from Institut Pasteur, and researchers from both groups will jointly develop the new vaccine | | Koronis Pharmaceuticals, Inc. announces the initiation of a Phase 1B clinical trial of KP-1461, an anti-viral therapeutic, in HIV-positive patients. The objectives of the trial are to evaluate the safety, toxicity, pharmacokinetic profile, and initial clinical activity of KP-1461. Unlike currently approved anti-HIV drugs that work to inhibit the HIV-virus by suppressing its replication, KP-1461 is designed to generate a high rate of mutation that is lethal to the virus | | On Wednesday, Koronis Pharmaceuticals, Inc. announces the initiation of a Phase 1B clinical trial of KP-1461, an anti-viral therapeutic, in HIV-positive patients. The objectives of the trial are to evaluate the safety, toxicity, pharmacokinetic profile and initial clinical activity of KP-1461. Unlike currently approved anti-HIV drugs that work to inhibit the HIV-virus by suppressing its replication, KP-1461 is designed to generate a high rate of mutation that is lethal to the virus | |
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