A bird flu pandemic could cost the global economy up to $800 billion USD warns the World Bank.

It is "only a matter of time" until the deadly H5N1 virus becomes capable of human to human transmission and causes global chaos, the head of the World Health Organization (WHO) says.

Presenting a report to the conference, the World Bank says that $800 billion USD amounted to 2 percent of the global economy.

The World Bank proposed to fund $500m of grants and aid to countries hit by a pandemic, and hopes to raise a similar sum through donations.

"It is fair to assume the shock during a flu epidemic could be even larger and last longer than Sars," says Milan Brahmbhatt, World Bank chief economist for the Asia-Pacific region.