Nearly 400 have been infected, officials said Monday.
Health Minister Makwenge Kaput said on national television the virus is the Ebola hemorrhagic fever, and Mweka and Luebo are the two most affected areas.
Jean-Constatin Kanow, the chief medical inspector for the province told the Associated Press: "The number of sick continues to climb, but the deaths are decreasing because they are being taken care of by medical teams on the ground."
There are no reports whether or not the outbreak has been contained in the region.
Ebola hemorrhagic fever (Ebola HF) is a severe, often-fatal disease in humans and nonhuman primates (monkeys, gorillas, and chimpanzees) that has appeared sporadically since its initial recognition in 1976.
All forms of viral hemorrhagic fever begin with fever and muscle aches, with the cause of death usually due to organ failure.
Health inspectors in Congo previously reported that people began dying after high-profile funerals of two village chiefs in the region where relatives usually wash the bodies of the deceased by hand.
Officials are still investigating the source of the initial infection and there is a speculation that it likely came from contact with an infected animal.
The Ebola virus spreads through direct contact with blood or bodily fluids of an infected person, or contaminated objects.
Congo has seen large outbreaks of Marburg and Ebola in the past. Both outbreaks are hemorrhagic fevers caused by viruses. The virus attacks the central nervous system, and cause bleeding from the eyes, ears and other parts of the body.
Nearly 217 people in four villages in Congo had been affected by Ebola by the end of August. It includes 103 people who died.
Earlier in 1995, nearly 245 people were killed in Kikwit due to Ebola. Kikwit is about 185 miles from the site of the current outbreak of the virus.
