New research shows the popular pain reliever Celebrex may pose a danger to the heart. Doctors have long prescribed the medicine to prevent colorectal polyps, which can lead to cancer.

In two studies, doctors studied whether the drug would prevent polyps from reappearing after having them removed. Celebrex was successful in preventing the growth of advanced polyps.

But the drug also doubled the risk of cardiovascular problems, including heart attacks, strokes, heart failure and even, death.

Doctors don't know why the connection, though they did note that the doseage seemed to affect its safety. Patients who took it twice a day had elevated blood pressure, those who took it once a day did not.